Lectin Pathway Enzyme MASP-2 and Downstream Complement Activation in COVID-19

• Main Authors: Maximilian Peter Götz (Author), Mikkel-Ole Skjoedt (Author), Rafael Bayarri-Olmos (Author), Cecilie Bo Hansen (Author), Laura Pérez-Alós (Author), Ida Jarlhelt (Author), Thomas Benfield (Author), Anne Rosbjerg (Author), Peter Garred (Author)
• Format: Book
• Published: Karger Publishers, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mannose-binding lectin-associated serine protease 2 (MASP-2) is the main activator of the lectin complement pathway and has been suggested to be involved in the pathophysiology of coronavirus disease 2019 (COVID-19). To study a possible association between MASP-2 and COVID-19, we aimed at developing...