Utility of Maternal 6-Thioguanine Nucleotide Levels in Predicting Neonatal Pancytopenia

• Main Authors: Hidehiko Maruyama (Author), Katsuhiko Tada (Author), Takuzo Fujiwara (Author), Kosuke Ota (Author), Misao Kageyama (Author)
• Format: Book
• Published: Thieme Medical Publishers, Inc., 2013-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract An infant with pancytopenia was born to a mother who used the common immunosuppressant azathioprine (AZA). Maternal and neonatal blood levels of 6-thioguanine nucleotides (6TGN; metabolite of AZA) were 1890 and 1480 pmol/8 × 108 red blood cells, respectively. Maternal 6TGN levels could be u...