LC-MS/MS assay for olanzapine in human plasma and its application to a bioequivalence study

• Hlavní autoři: Dinesh S. Patel (Autor), Naveen Sharma (Autor), Mukesh C. Patel (Autor), Bhavin N. Patel (Autor), Pranav S. Shrivastav (Autor), Mallika Sanyal (Autor)
• Médium: Kniha
• Vydáno: Elsevier, 2012-10-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

This paper describes a selective and sensitive assay for the determination of olanzapine (OLZ) in human plasma based on liquid chromatography-tandem mass spectrometry (LC-MS/MS). The analyte and quetiapine as internal standard (IS) were extracted from 200 μL plasma via solid phase extraction on Wate...