Feasibility and diagnostic benefit of increased cerebrospinal fluid volume and frequency in the diagnosis of tuberculous meningitis

• Main Authors: Sheena Evelyn Ebenezer (Author), Ramya Iyyadurai (Author), Joy Sarojini Michael (Author), O C Abraham (Author), Sowmya Satyendra Sudha Jasmine (Author), K P P Abhihash (Author), Jayaprakash Muliyil (Author), Thambu David Sudarsanam (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Definite diagnosis of tuberculous meningitis (TBM) requires demonstration of TB bacilli in the cerebrospinal fluid (CSF) on smear, culture, or nucleic acid amplification. However, the sensitivity of these tests is low. This study was done to see if smear and culture done on a larger volu...