The Botanical Drug PBI-05204, a Supercritical CO2 Extract of Nerium Oleander, Is Synergistic With Radiotherapy in Models of Human Glioblastoma

• Main Authors: Alessandro Colapietro (Author), Peiying Yang (Author), Alessandra Rossetti (Author), Andrea Mancini (Author), Flora Vitale (Author), Sharmistha Chakraborty (Author), Stefano Martellucci (Author), Francesco Marampon (Author), Vincenzo Mattei (Author), Giovanni Luca Gravina (Author), Roberto Iorio (Author), Robert A. Newman (Author), Claudio Festuccia (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Glioblastoma multiforme (GBM) is the most common as well as one of the most malignant types of brain cancer. Despite progress in development of novel therapies for the treatment of GBM, it remains largely incurable with a poor prognosis and a very low life expectancy. Recent studies have shown that...