PBPK‐led assessment of antimalarial drugs as candidates for Covid‐19: Simulating concentrations at the site of action to inform repurposing strategies
Abstract The urgent need for safe, efficacious, and accessible drug treatments to treat coronavirus disease 2019 (COVID‐19) prompted a global effort to evaluate drug repurposing opportunities. Pyronaridine and amodiaquine are both components of approved antimalarials with in vitro activity against s...
Saved in:
Main Authors: | Nada Abla (Author), Lisa M. Almond (Author), Jennifer J. Bonner (Author), Naomi Richardson (Author), Timothy N. C. Wells (Author), Jörg J. Möhrle (Author) |
---|---|
Format: | Book |
Published: |
Wiley,
2024-07-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Development and application of a PBPK modeling strategy to support antimalarial drug development
by: Nada Abla, et al.
Published: (2023) -
Repurposing the antimalarial pyronaridine tetraphosphate to protect against Ebola virus infection.
by: Thomas R Lane, et al.
Published: (2019) -
Repurposing Heparin as Antimalarial: Evaluation of Multiple Modifications Toward In Vivo Application
by: Elena Lantero, et al.
Published: (2020) -
Candidate drug repurposing for malaria: perspectives for optimising clinical trials
by: J. Luis Espinoza
Published: (2025) -
Antimalarial efficacy and toxicological assessment of medicinal plant ingredients of Prabchompoothaweep remedy as a candidate for antimalarial drug development
by: Prapaporn Chaniad, et al.
Published: (2023)