Cell-penetrating peptide conjugates to enhance the antitumor effect of paclitaxel on drug-resistant lung cancer

• Asıl Yazarlar: Ziqing Duan (Yazar), Cuitian Chen (Yazar), Jing Qin (Yazar), Qi Liu (Yazar), Qi Wang (Yazar), Xinchun Xu (Yazar), Jianxin Wang (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

To conquer the drug resistance of tumors and the poor solubility of paclitaxel (PTX), two PTX-cell-penetrating peptide conjugates (PTX-CPPs), PTX-TAT and PTX-LMWP, were synthesized and evaluated for the first time. Compared with free PTX, PTX-CPPs displayed significantly enhanced cellular uptake, el...