Resistance of M. leprae to quinolones: a question of relativity?

• Hauptverfasser: Nicolas Veziris (Verfasst von), Aurélie Chauffour (Verfasst von), Sylvie Escolano (Verfasst von), Sarah Henquet (Verfasst von), Masanori Matsuoka (Verfasst von), Vincent Jarlier (Verfasst von), Alexandra Aubry (Verfasst von)
• Format: Buch
• Veröffentlicht: Public Library of Science (PLoS), 2013-11-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

UNLABELLED:Multidrug resistant leprosy, defined as resistance to rifampin, dapsone and fluoroquinolones (FQ), has been described in Mycobacterium leprae. However, the in vivo impact of fluoroquinolone resistance, mainly mediated by mutations in DNA gyrase (GyrA2GyrB2), has not been precisely assesse...