Resistance of M. leprae to quinolones: a question of relativity?

• Main Authors: Nicolas Veziris (Author), Aurélie Chauffour (Author), Sylvie Escolano (Author), Sarah Henquet (Author), Masanori Matsuoka (Author), Vincent Jarlier (Author), Alexandra Aubry (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2013-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

UNLABELLED:Multidrug resistant leprosy, defined as resistance to rifampin, dapsone and fluoroquinolones (FQ), has been described in Mycobacterium leprae. However, the in vivo impact of fluoroquinolone resistance, mainly mediated by mutations in DNA gyrase (GyrA2GyrB2), has not been precisely assesse...