Lipoxygenase Inhibition Activity of Coumarin Derivatives-QSAR and Molecular Docking Study

• Main Authors: Melita Lončarić (Author), Ivica Strelec (Author), Valentina Pavić (Author), Domagoj Šubarić (Author), Vesna Rastija (Author), Maja Molnar (Author)
• Format: Book
• Published: MDPI AG, 2020-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Lipoxygenases (LOXs) are a family of enzymes found in plants, mammals, and microorganisms. In animals and plants, the enzyme has the capability for the peroxidation of unsaturated fatty acids. Although LOXs participate in the plant defense system, the enzyme's metabolites can have numerous nega...