Concept of ecologically acceptable chromatographic methods: Case study on the separation of dronedarone hydrochloride and its degradation products

• Main Authors: Đajić Nevena (Author), Krmar Jovana (Author), Stojanović Jevrem (Author), Svrkota Bojana (Author), Otašević Biljana (Author), Malenović Anđelija (Author), Protić Ana (Author)
• Format: Book
• Published: Pharmaceutical Association of Serbia, Belgrade, Serbia, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Recently, concern about the environmental impact of drug analysis methods has increased significantly. Reversed-phase high-performance liquid chromatography (RP-HPLC), the predominant technique in drug analysis, relies heavily on organic solvents such as acetonitrile, which is known for its chromato...