Undercover Toxic Ménage à Trois of Amylin, Copper (II) and Metformin in Human Embryonic Kidney Cells

• Egile Nagusiak: Terenzio Congiu (Egilea), Mawadda Alghrably (Egilea), Abdul-Hamid Emwas (Egilea), Lukasz Jaremko (Egilea), Joanna I. Lachowicz (Egilea), Marco Piludu (Egilea), Monica Piras (Egilea), Gavino Faa (Egilea), Giuseppina Pichiri (Egilea), Mariusz Jaremko (Egilea), Pierpaolo Coni (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2021-06-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

In recent decades, type 2 diabetes complications have been correlated with amylin aggregation, copper homeostasis and metformin side effects. However, each factor was analyzed separately, and only in some rare cases copper/amylin or copper/metformin complexes were considered. We demonstrate for the...