Undercover Toxic Ménage à Trois of Amylin, Copper (II) and Metformin in Human Embryonic Kidney Cells

• Main Authors: Terenzio Congiu (Author), Mawadda Alghrably (Author), Abdul-Hamid Emwas (Author), Lukasz Jaremko (Author), Joanna I. Lachowicz (Author), Marco Piludu (Author), Monica Piras (Author), Gavino Faa (Author), Giuseppina Pichiri (Author), Mariusz Jaremko (Author), Pierpaolo Coni (Author)
• Format: Book
• Published: MDPI AG, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In recent decades, type 2 diabetes complications have been correlated with amylin aggregation, copper homeostasis and metformin side effects. However, each factor was analyzed separately, and only in some rare cases copper/amylin or copper/metformin complexes were considered. We demonstrate for the...