The association between genetic variants in <it>hMLH1 </it>and <it>hMSH2 </it>and the development of sporadic colorectal cancer in the Danish population

• Main Authors: Syvänen Ann-Christine (Author), Olsen Anja (Author), Tjønneland Anne (Author), Koed Karen (Author), Wiuf Carsten (Author), Wikman Friedrik P (Author), Madsen Bo E (Author), Christensen Lise (Author), Andersen Claus L (Author), Ørntoft Torben F (Author)
• Format: Book
• Published: BMC, 2008-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Mutations in the mismatch repair genes <it>hMLH1 </it>and <it>hMSH2 </it>predispose to hereditary non-polyposis colorectal cancer (HNPCC). Genetic screening of more than 350 Danish patients with colorectal can...