The association between genetic variants in <it>hMLH1 </it>and <it>hMSH2 </it>and the development of sporadic colorectal cancer in the Danish population

• 主要な著者: Syvänen Ann-Christine (著者), Olsen Anja (著者), Tjønneland Anne (著者), Koed Karen (著者), Wiuf Carsten (著者), Wikman Friedrik P (著者), Madsen Bo E (著者), Christensen Lise (著者), Andersen Claus L (著者), Ørntoft Torben F (著者)
• フォーマット: 図書
• 出版事項: BMC, 2008-06-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Mutations in the mismatch repair genes <it>hMLH1 </it>and <it>hMSH2 </it>predispose to hereditary non-polyposis colorectal cancer (HNPCC). Genetic screening of more than 350 Danish patients with colorectal can...