MicroRNAs and Their Therapeutic Potential for Human Diseases: MiR-133a and Bronchial Smooth Muscle Hyperresponsiveness in Asthma

Abstract.: MicroRNAs (miRNAs) play important roles in normal and diseased cell functions. The small-GTPase RhoA is one of the key proteins of bronchial smooth muscle (BSM) contraction, and an upregulation of RhoA has been demonstrated in BSMs of experimental asthma. Although the mechanism of RhoA up...

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Bibliographic Details
Main Authors: Yoshihiko Chiba (Author), Miwa Misawa (Author)
Format: Book
Published: Elsevier, 2010-01-01T00:00:00Z.
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