Integration of network pharmacology and intestinal flora to investigate the mechanism of action of Chinese herbal Cichorium intybus formula in attenuating adenine and ethambutol hydrochloride-induced hyperuricemic nephropathy in rats

• Main Authors: Na Li (Author), Mukaram Amatjan (Author), Pengke He (Author), Boheng Zhang (Author), Xianyan Mai (Author), Qianle Jiang (Author), Haochen Xie (Author), Xiaoni Shao (Author)
• Format: Book
• Published: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Context Cichorium intybus L. (Asteraceae) formula (CF) has been applied as a folk medicine to treat hyperuricemic nephropathy (HN). However, the exact mechanism remains unclear.Objective To explore the therapeutic effect and mechanism of CF on HN.Materials and methods Through network pharmacological...