Pharmacokinetic evaluation, molecular docking and in vitro biological evaluation of 1, 3, 4-oxadiazole derivatives as potent antioxidants and STAT3 inhibitors

• المؤلفون الرئيسيون: Rashmin khanam (مؤلف), Iram I. Hejazi (مؤلف), Syed Shahabuddin (مؤلف), Abdul R. Bhat (مؤلف), Fareeda Athar (مؤلف)
• التنسيق: كتاب
• منشور في: Elsevier, 2019-04-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

1, 3, 4-Oxadiazole derivatives (4a-5f) were previously synthesized to investigate their anticancer properties. However, studies relating to their antioxidant potential and signal transducer and activator of transcription (STAT) inhibition have not been performed. We investigated previously synthesiz...