Paracrine Neuroprotective Effects of Neural Stem Cells on Glutamate-Induced Cortical Neuronal Cell Excitotoxicity

• Main Authors: Mohammad Hossein Geranmayeh (Author), Ali Baghbanzadeh (Author), Abbas Barin (Author), Jamileh Salar-Amoli (Author), Mohammad Mehdi Dehghan (Author), Reza Rahbarghazi (Author), Hassan Azari (Author)
• Format: Book
• Published: Tabriz University of Medical Sciences, 2015-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: Glutamate is a major excitatory neurotransmitter in mammalian central nervous system. Excessive glutamate releasing overactivates its receptors and changes calcium homeostasis that in turn leads to a cascade of intracellular events causing neuronal degeneration. In current study, we used ne...