Exogenous H2S promotes ubiquitin‐mediated degradation of SREBP1 to alleviate diabetic cardiomyopathy via SYVN1 S‐sulfhydration

• Main Authors: Shiwu Zhang (Author), Mengyi Wang (Author), Hongxia Li (Author), Qianzhu Li (Author), Ning Liu (Author), Shiyun Dong (Author), Yajun Zhao (Author), Kemiao Pang (Author), Jiayi Huang (Author), Cheng Ren (Author), Yan Wang (Author), Zhen Tian (Author), Fanghao Lu (Author), Weihua Zhang (Author)
• Format: Book
• Published: Wiley, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Diabetic cardiomyopathy, a distinctive complication of diabetes mellitus, has been correlated with the presence of intracellular lipid deposits. However, the intricate molecular mechanisms governing the aberrant accumulation of lipid droplets within cardiomyocytes remain to be co...