Pichia pastoris secreted peptides crossing the blood-brain barrier and DSIP fusion peptide efficacy in PCPA-induced insomnia mouse models

• Главные авторы: Xiaoxiao Mu (Автор), Lijun Qu (Автор), Liquan Yin (Автор), Libo Wang (Автор), Xiaoyang Liu (Автор), Dingxi Liu (Автор)
• Формат: ‌
• Опубликовано: Frontiers Media S.A., 2024-10-01T00:00:00Z.
• Предметы: article
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BackgroundPichia pastoris-secreted delta sleep inducing peptide and crossing the blood-brain barrier peptides (DSIP-CBBBP) fusion peptides holds significant promise for its potential sleep-enhancing and neurotransmitter balancing effects. This study investigates these properties using a p-chlorophen...