Association Between Arg753Gln and Arg677Trp Polymorphisms of TLR2 Gene with Active Pulmonary Tuberculosis in an Indonesian Population

• Главные авторы: Arto Yuwono Soeroto (Автор), Zulkarnain Dahlan (Автор), Cissy B Kartasasmita (Автор), Ida Parwati (Автор)
• Формат: ‌
• Опубликовано: Interna Publishing, 2018-04-01T00:00:00Z.
• Предметы: article
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Background: Toll-like receptor is a pattern recognition receptor (PRR) that recognize pathogen-associated molecular pattern (PAMP) in a microorganism. Macrophages recognize the presence of mycobacteria through Toll-Like Receptor 2 (TLR2) and signaling further lead to the production of cytokines, bot...