Association Between Arg753Gln and Arg677Trp Polymorphisms of TLR2 Gene with Active Pulmonary Tuberculosis in an Indonesian Population

• Główni autorzy: Arto Yuwono Soeroto (Autor), Zulkarnain Dahlan (Autor), Cissy B Kartasasmita (Autor), Ida Parwati (Autor)
• Format: Książka
• Wydane: Interna Publishing, 2018-04-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Background: Toll-like receptor is a pattern recognition receptor (PRR) that recognize pathogen-associated molecular pattern (PAMP) in a microorganism. Macrophages recognize the presence of mycobacteria through Toll-Like Receptor 2 (TLR2) and signaling further lead to the production of cytokines, bot...