Transdifferentiation of α-1,3-Galactosyltransferase Knock Out (GalT KO) Pig Derived Bone Marrow Mesenchymal Stromal Cells (BM-MSCs) into Pancreatic Cells by Transfection of hPDX1

• Main Authors: Sun A Ock (Author), Keon Bong Oh (Author), Seongsoo Hwang (Author), Youngim Kim (Author), Dae-Jin Kwon (Author), Gi-Sun Im (Author)
• Format: Book
• Published: The Korean Society of Animal Reproduction and Biotechnology, 2015-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Diabetes mellitus, the most common metabolic disorder, is divided into two types: type 1 and type 2. The essential treatment of type 1 diabetes, caused by immune-mediated destruction of β-cells, is transplantation of the pancreas; however, this treatment is limited by issues such as the lack of dono...