Augmented Efficacy of Uttroside B over Sorafenib in a Murine Model of Human Hepatocellular Carcinoma

• Главные авторы: Mundanattu Swetha (Автор), Chenicheri K. Keerthana (Автор), Tennyson P. Rayginia (Автор), Lekshmi R. Nath (Автор), Nair Hariprasad Haritha (Автор), Anwar Shabna (Автор), Kalishwaralal Kalimuthu (Автор), Arun K. Thangarasu (Автор), Sreekumar U. Aiswarya (Автор), Somaraj Jannet (Автор), Sreekumar Pillai (Автор), Kuzhuvelil B. Harikumar (Автор), Sankar Sundaram (Автор), Nikhil Ponnoor Anto (Автор), Dee H. Wu (Автор), Ravi S. Lankalapalli (Автор), Rheal Towner (Автор), Noah Isakov (Автор), Sathyaseelan S. Deepa (Автор), Ruby John Anto (Автор)
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• Опубликовано: MDPI AG, 2022-05-01T00:00:00Z.
• Предметы: article
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We previously reported the remarkable potency of uttroside B (Utt-B), saponin-isolated and characterized in our lab from <i>Solanum nigrum</i> Linn, against HCC. Recently, the U.S. FDA approved Utt-B as an 'orphan drug' against HCC. The current study validates the superior anti...