Downregulation of Iron-Sulfur Cluster Biogenesis May Contribute to Hyperglycemia-Mediated Diabetic Peripheral Neuropathy in Murine Models

• Main Authors: Lin Wu (Author), Fei Huang (Author), Zichen Sun (Author), Jinghua Zhang (Author), Siyu Xia (Author), Hongting Zhao (Author), Yutong Liu (Author), Lu Yang (Author), Yibing Ding (Author), Dezhi Bian (Author), Kuanyu Li (Author), Yu Sun (Author)
• Format: Book
• Published: MDPI AG, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Diabetic peripheral neuropathy (DPN) is considered one of the most common chronic complications of diabetes. Impairment of mitochondrial function is regarded as one of the causes. Iron-sulfur clusters are essential cofactors for numerous iron-sulfur (Fe-S)-containing proteins/enzymes, in...