Soluble PD1 levels are increased with disease activity in paediatric onset autoimmune hepatitis and inflammatory bowel disease

• Main Authors: Timothy Hadley (Author), Scott Gillespie (Author), Hillary Espinoza (Author), Jarod Prince (Author), Henning Gronbaek (Author), Shanmuganathan Chandrakasan (Author), Subra Kuguthasan (Author), Vasantha L. Kolachala (Author), Nitika A. Gupta (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Immune mediated liver diseases entail a broad category which are associated with increased morbidity and mortality amongst the paediatric population. Programmed Death 1 (PD1) is an inhibitory receptor mainly expressed by T cells, and when activated shed into plasma as soluble PD1(sPD1)...