Analysis of original bis-arylazaazkanes derivatives compliance with the calculated pharmacophoric models of biaromatic ligands of cardioprotective drugs biotargets

• Главные авторы: G. V. Mokrov (Автор), A. S. Pantileev (Автор), T. Yu. Vorobieva (Автор), V. E. Biryukova (Автор), S. A. Kryzhanovskii (Автор), V. L. Dorofeev (Автор)
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• Опубликовано: LLC "Publisher OKI", 2024-06-01T00:00:00Z.
• Предметы: article
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Eight important biotargets of biaromatic cardioprotective drugs were selected in this work: calcium Cav1.2-channel, sodium Nav1.5-channel, potassium hERG-channel and Kv1.5-channel, HCN-channel, β1-adrenergic receptor, ryanodine RyR2-receptor and σ1-receptor. Biaromatic ligands databases were collect...