Role of Secretory Phospholipase A2 in Rhythmic Contraction of Pulmonary Arteries of Rats With Monocrotaline-Induced Pulmonary Arterial Hypertension

• Główni autorzy: Yoshiyuki Tanabe (Autor), Maki Saito-Tanji (Autor), Yuki Morikawa (Autor), Akihisa Kamataki (Autor), Takashi Sawai (Autor), Koichi Nakayama (Autor)
• Format: Książka
• Wydane: Elsevier, 2012-01-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Excessive stretching of the vascular wall in accordance with pulmonary arterial hypertension (PAH) induces a variety of pathogenic cellular events in the pulmonary arteries. We previously reported that indoxam, a selective inhibitor for secretory phospholipase A2 (sPLA2), blocked the stretch-induced...