C-1 Substituted isoquinolines potentiate the antimycobacterial activity of rifampicin and ethambutol

• Main Authors: Liam T. Martin (Author), Eleanor D. Lamming (Author), Arundhati Maitra (Author), Parisa N. Mortazavi (Author), Rebecca Roddan (Author), John M. Ward (Author), Sanjib Bhakta (Author), Helen C. Hailes (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

IntroductionThe emergence of extensively drug-resistant strains of Mycobacterium tuberculosis threatens decades of progress in the treatment of a disease which remains one of the leading infectious causes of death worldwide. The development of novel antimycobacterial compounds is therefore essential...