Human Organic Anion Transporter 4 Is a Renal Apical Organic Anion/Dicarboxylate Exchanger in the Proximal Tubules

• Main Authors: Sophapun Ekaratanawong (Author), Naohiko Anzai (Author), Promsuk Jutabha (Author), Hiroki Miyazaki (Author), Rie Noshiro (Author), Michio Takeda (Author), Yoshikatsu Kanai (Author), Samaisukh Sophasan (Author), Hitoshi Endou (Author)
• Format: Book
• Published: Elsevier, 2004-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Human organic anion transporter OAT4 is expressed in the kidney and placenta and mediates high-affinity transport of estrone-3-sulfate (E1S). Because a previous study demonstrated no trans-stimulatory effects by E1S, the mode of organic anion transport via OAT4 remains still unclear. In the present...