Perceiving the Concealed and Unreported Pharmacophoric Features of the 5-Hydroxytryptamine Receptor Using Balanced QSAR Analysis

• Main Authors: Syed Nasir Abbas Bukhari (Author), Mervat Abdelaziz Elsherif (Author), Kashaf Junaid (Author), Hasan Ejaz (Author), Pravej Alam (Author), Abdul Samad (Author), Rahul D. Jawarkar (Author), Vijay H. Masand (Author)
• Format: Book
• Published: MDPI AG, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The 5-hydroxytryptamine receptor 6 (5-HT6) has gained attention as a target for developing therapeutics for Alzheimer's disease, schizophrenia, cognitive dysfunctions, anxiety, and depression, to list a few. In the present analysis, a larger and diverse dataset of 1278 molecules covering a broa...