The andrographolide derivative, AND7, and TRAIL combination attenuates acute lymphoblastic leukemia through P53-regulated ROS accumulation

• Main Authors: Letian Xu (Author), Yuting Zhou (Author), Rui Ma (Author), Xinqin Guo (Author), Hao Chen (Author), Lei Fan (Author), Xiaoming Wang (Author)
• Format: Book
• Published: Compuscript Ltd, 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Acute lymphoblastic leukemia (ALL) is a malignant disease of the hematologic system. The current treatment is based on chemotherapeutic drugs, which are becoming less effective due to drug resistance. TNF-related apoptosis-inducing ligand (TRAIL) is an apoptotic protein used to treat cancer that doe...