Nasal irrigation with licorice extract (Glycyrrhiza glabra) in treating nasal polyps by reducing fibroblast differentiation and extracellular matrix production in TGF-β1-stimulated nasal polyp-derived fibroblasts by inhibiting the MAPK/ERK-1/2 pathway - an in vitro and in clinic study

• Main Authors: Geng-He Chang (Author), Pei-Rung Yang (Author), Yu-Ching Cheng (Author), Ke-Hsin Hsu (Author), Ching-Yuan Wu (Author), Yao-Hsu Yang (Author), Yu-Shih Lin (Author), Cheng-Ming Hsu (Author), Ming-Shao Tsai (Author), Yao-Te Tsai (Author), Pey-Jium Chang (Author)
• Format: Book
• Published: BMC, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background To date, treating nasal polyps (NPs) is still a medical challenge. However, we have developed an innovative therapy using licorice extract (LE: Glycyrrhiza glabra) to treat rhinitis and sinusitis via nasal irrigation and have discovered that it significantly affects treatment of...