The RS4939827 polymorphism in the SMAD7 GENE and its association with Mediterranean diet in colorectal carcinogenesis

• Main Authors: Jéssica Alonso-Molero (Author), Carmen González-Donquiles (Author), Camilo Palazuelos (Author), Tania Fernández-Villa (Author), Elena Ramos (Author), Marina Pollán (Author), Nuria Aragonés (Author), Javier Llorca (Author), M. Henar Alonso (Author), Adonina Tardón (Author), Pilar Amiano (Author), José Juan Jiménez Moleon (Author), Rosana Peiró Pérez (Author), Rocío Capelo (Author), Antonio J. Molina (Author), Inés Gómez Acebo (Author), Marcela Guevara (Author), Beatriz Perez-Gomez (Author), Virginia Lope (Author), José María Huerta (Author), Gemma Castaño-Vinyals (Author), Manolis Kogevinas (Author), Victor Moreno (Author), Vicente Martín (Author)
• Format: Book
• Published: BMC, 2017-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The objective of our investigation is to study the relationship between the rs4939827 SNP in the SMAD7 gene, Mediterranean diet pattern and the risk of colorectal cancer. Methods We examined 1087 cases of colorectal cancer and 2409 population controls with available DNA samples f...