Serum Peak Sulfamethoxazole Concentrations Demonstrate Difficulty in Achieving a Target Range: A Retrospective Cohort Study

Serum Peak Sulfamethoxazole Concentrations Demonstrate Difficulty in Achieving a Target Range: A Retrospective Cohort Study

Objectives: Trimethoprim (TMP)/sulfamethoxazole (SMX) has consistently demonstrated great interindividual variability. Therapeutic drug monitoring may be used to optimize dosing. Optimal peak SMX concentration has been proposed as 100 to 150 μg/mL. The objective of our work was to determine the succ...

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Main Authors: Bao D. Dao, PharmD (Author), Jason N. Barreto, PharmD (Author), Robert C. Wolf, PharmD (Author), Ross A. Dierkhising, MS (Author), Matthew F. Plevak, BS (Author), Pritish K. Tosh, MD (Author)
Format: Book
Published: Elsevier, 2014-12-01T00:00:00Z.
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