Development of a particle swarm optimization-backpropagation artificial neural network model and effects of age and gender on pharmacokinetics study of omeprazole enteric-coated tablets in Chinese population

• Autores principales: Yichao Xu (Autor), Jinliang Chen (Autor), Dandan Yang (Autor), Yin Hu (Autor), Bo Jiang (Autor), Zourong Ruan (Autor), Honggang Lou (Autor)
• Formato: Libro
• Publicado: BMC, 2022-07-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Abstract Background The effects of age and gender were explored on pharmacokinetics study of omeprazole enteric-coated tablets in Chinese population and a plasma concentration prediction model was developed. All the data (demographic characteristics and results of clinical laboratory tests) were col...