Glycyrrhizin Attenuates Mucus Production by Inhibition of MUC5AC mRNA Expression In Vivo and In Vitro

• Main Authors: Yuki Nishimoto (Author), Akinori Hisatsune (Author), Hiroshi Katsuki (Author), Takeshi Miyata (Author), Kazumi Yokomizo (Author), Yoichiro Isohama (Author)
• Format: Book
• Published: Elsevier, 2010-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We have previously indicated that glycyrrhizin (GL), a major component of licorice, has glucocorticoid-like anti-inflammatory effects in cultured airway epithelial cells and suggested its usefulness in the treatment of inflammatory respiratory diseases. On the other hand, mucus hypersecretion in the...