Prostaglandin metabolite induces inhibition of TRPA1 and channel-dependent nociception

• Autores principales: Weng Yingqi (Autor), Batista-Schepman Patricia A (Autor), Barabas Marie E (Autor), Harris Eli Q (Autor), Dinsmore Thomas B (Autor), Kossyreva Elena A (Autor), Foshage Audra M (Autor), Wang Michelle H (Autor), Schwab Matthew J (Autor), Wang Victoria M (Autor), Stucky Cheryl L (Autor), Story Gina M (Autor)
• Formato: Libro
• Publicado: SAGE Publishing, 2012-09-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>The Transient Receptor Potential (TRP) ion channel TRPA1 is a key player in pain pathways. Irritant chemicals activate ion channel TRPA1 via covalent modification of N-terminal cysteines. We and others have shown that 15-Deoxy-Δ12, 1...