Dengue virus infection-enhancing activity in serum samples with neutralizing activity as determined by using FcγR-expressing cells.

BACKGROUND: Progress in dengue vaccine development has been hampered by limited understanding of protective immunity against dengue virus infection. Conventional neutralizing antibody titration assays that use FcγR-negative cells do not consider possible infection-enhancement activity. We reasoned t...

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Main Authors: Meng Ling Moi (Author), Chang-Kweng Lim (Author), Kaw Bing Chua (Author), Tomohiko Takasaki (Author), Ichiro Kurane (Author)
Format: Book
Published: Public Library of Science (PLoS), 2012-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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