In vivo neural regeneration via AAV-NeuroD1 gene delivery to astrocytes in neonatal hypoxic-ischemic brain injury

• Main Authors: Miri Kim (Author), Seokmin Oh (Author), Songyeon Kim (Author), Il-Sun Kim (Author), Joowon Kim (Author), Jungho Han (Author), Ji Woong Ahn (Author), Seungsoo Chung (Author), Jae-Hyung Jang (Author), Jeong Eun Shin (Author), Kook In Park (Author)
• Format: Book
• Published: BMC, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Neonatal hypoxic-ischemic brain injury (HIBI) is a significant contributor to neonatal mortality and long-term neurodevelopmental disability, characterized by massive neuronal loss and reactive astrogliosis. Current therapeutic approaches for neonatal HIBI have been limited to ge...