Deamidation-related blood biomarkers show promise for early diagnostics of neurodegeneration
Abstract Background The strongest risk factor of neurodegenerative diseases (NDDs) is aging. Spontaneous asparaginyl deamidation leading to formation of isoaspartate (isoAsp) has been correlated with protein aggregation in NDDs. Methods Two cohorts consisting of 140 subjects were studied. Cohort 1 c...
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| Main Authors: | , , , , , , , , |
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| Format: | Book |
| Published: |
BMC,
2022-12-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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