Injectable hyaluronic acid hydrogels encapsulating drug nanocrystals for long‐term treatment of inflammatory arthritis

• Main Authors: Yongsheng Gao (Author), Douglas Vogus (Author), Zongmin Zhao (Author), Wei He (Author), Vinu Krishnan (Author), Jayoung Kim (Author), Yujie Shi (Author), Apoorva Sarode (Author), Anvay Ukidve (Author), Samir Mitragotri (Author)
• Format: Book
• Published: Wiley, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Antiproliferative chemotherapeutic agents offer a potential effective treatment for inflammatory arthritis. However, their clinical application is limited by high systemic toxicity, low joint bioavailability as well as formulation challenges. Here, we report an intra‐articular drug delivery...