Measurement of complement activation via plasma soluble C5b-9 comparison with terminal complement complex staining in a series of kidney biopsies

• Main Authors: Carolyn Wijaya (Author), Christine Burns (Author), Sharron Hall (Author), Melissa Farmer (Author), Denise Jones (Author), Matthew Rowlandson (Author), Peter Choi (Author), Mark Formby (Author), Theo de Malmanche (Author)
• Format: Book
• Published: Karger Publishers, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: With the emergence of therapeutic complement inhibitors, there is a need to identify patients with complement-driven inflammation. C5b-9 is the terminal product of the three complement pathways, and therefore a marker of total complement activation. We present a pilot study which aims...