Targeting CD38/ ADP-ribosyl cyclase as a novel therapeutic strategy for identification of three potent agonists for leukopenia treatment

• Main Authors: Yuanzhi Liu (Author), Linwei Zhang (Author), Long Wang (Author), Xiaoqin Tang (Author), Shengli Wan (Author), Qianqian Huang (Author), Mei Ran (Author), Hongping Shen (Author), Yan Yang (Author), Sawitree Chiampanichayakul (Author), Singkome Tima (Author), Songyot Anuchapreeda (Author), Jianming Wu (Author)
• Format: Book
• Published: Elsevier, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Leukopenia is the most common side effect of chemotherapy and radiotherapy. It potentially deteriorates into a life-threatening complication in cancer patients. Despite several agents being approved for clinical administration, there are still high incidences of pathogen-related disease due to a lac...