Evaluation of risk for graft-versus-host disease in children who receive less than the full doses of mini-dose methotrexate for graft-versus-host disease prophylaxis in allogeneic hematopoietic stem cell transplantation

• Main Authors: Sook Kyung Yum (Author), Hye-Yoon Choi (Author), Jae Wook Lee (Author), Pil-Sang Jang (Author), Nack-Gyun Chung (Author), Dae-Chul Jeong (Author), Bin Cho (Author), Hack-Ki Kim (Author)
• Format: Book
• Published: Korean Pediatric Society, 2013-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

PurposeThe use of cyclosporine and mini-dose methotrexate (MTX) is a common strategy for graft-versus-host disease (GVHD) prophylaxis in allogeneic transplants. We investigated whether patients who receive fewer than the planned MTX doses are at increased risk for GVHD.MethodsThe study cohort includ...