A synthetic peptide from Sipunculus nudus promotes bone formation via Estrogen/MAPK signal pathway based on network pharmacology

• Главные авторы: Peiran Wang (Автор), Zhenhui Feng (Автор), Siyu Chen (Автор), Yingye Liang (Автор), Haiyan Hou (Автор), Qianqian Ouyang (Автор), Hui Yu (Автор), Hua Ye (Автор), Lei Cai (Автор), Yi Qi (Автор), Kefeng Wu (Автор), Hui Luo (Автор)
• Формат: ‌
• Опубликовано: Frontiers Media S.A., 2023-04-01T00:00:00Z.
• Предметы: article
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The tripeptide Leu-Pro-Lys (LPK), derived from the Sipunculus nudus protein, was synthesized and studied to investigate its potential protective effect on bone formation. The effect and mechanism of LPK were analyzed through network pharmacology, bioinformatics, and experimental pharmacology. The st...