Protective Effect of Oxytocin on Ventilator-Induced Lung Injury Through NLRP3-Mediated Pathways

• Main Authors: Xiaomei Yang (Author), Xiaona An (Author), Cheng Wang (Author), Feng Gao (Author), Yicheng Lin (Author), Wenjing Chen (Author), Qiming Deng (Author), Dongsheng Xu (Author), Shengqiang Li (Author), Peng Zhang (Author), Baozhu Sun (Author), Yuedong Hou (Author), Jianbo Wu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mechanical ventilation is an indispensable life-support treatment for acute respiratory failure in critically ill patients, which is generally believed to involve uncontrolled inflammatory responses. Oxytocin (OT) has been reported to be effective in animal models of acute lung injury. However, it i...