Decreased N-TAF1 expression in X-linked dystonia-parkinsonism patient-specific neural stem cells

• Hlavní autoři: Naoto Ito (Autor), William T. Hendriks (Autor), Jyotsna Dhakal (Autor), Christine A. Vaine (Autor), Christina Liu (Autor), David Shin (Autor), Kyle Shin (Autor), Noriko Wakabayashi-Ito (Autor), Marisela Dy (Autor), Trisha Multhaupt-Buell (Autor), Nutan Sharma (Autor), Xandra O. Breakefield (Autor), D. Cristopher Bragg (Autor)
• Médium: Kniha
• Vydáno: The Company of Biologists, 2016-04-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

X-linked dystonia-parkinsonism (XDP) is a hereditary neurodegenerative disorder involving a progressive loss of striatal medium spiny neurons. The mechanisms underlying neurodegeneration are not known, in part because there have been few cellular models available for studying the disease. The XDP ha...