Role of abnormal glycosylated IgA1 and interstitial transformation of glomerular endothelial cells in the development and progression of IgA nephropathy

• Main Authors: Wanyu Jia (Author), Wenjie Dou (Author), Qin Wang (Author), Huiqin Zeng (Author), Peipei Shi (Author), Jing Liu (Author), Zhen Liu (Author), Jin Zhang (Author), Jian-Jiang Zhang (Author)
• Format: Book
• Published: BMC, 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background IgA nephropathy (IgAN) is a common primary renal disease in childhood. Methods Twenty blood samples and renal tissue from patients with IgAN, 20 blood samples from healthy children and 10 normal renal tissue were collected. Serum Gd-IgA1 and renal Gd-IgA1, CD31, α-SMA and vimenti...