AKT inhibitor Hu7691 induces differentiation of neuroblastoma cells

• Main Authors: Shaowei Bing (Author), Senfeng Xiang (Author), Zhimei Xia (Author), Yilong Wang (Author), Zhonghai Guan (Author), Jinxin Che (Author), Aixiao Xu (Author), Xiaowu Dong (Author), Ji Cao (Author), Bo Yang (Author), Jinhu Wang (Author), Qiaojun He (Author), Meidan Ying (Author)
• Format: Book
• Published: Elsevier, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

While neuroblastoma accounts for 15% of childhood tumor-related deaths, treatments against neuroblastoma remain scarce and mainly consist of cytotoxic chemotherapeutic drugs. Currently, maintenance therapy of differentiation induction is the standard of care for neuroblastoma patients in clinical, e...