Post-exposure therapeutic efficacy of COX-2 inhibition against Burkholderia pseudomallei.

• Main Authors: Saja Asakrah (Author), Wildaliz Nieves (Author), Zaid Mahdi (Author), Mallory Agard (Author), Arnold H Zea (Author), Chad J Roy (Author), Lisa A Morici (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Burkholderia pseudomallei is a Gram-negative, facultative intracellular bacillus and the etiologic agent of melioidosis, a severe disease in Southeast Asia and Northern Australia. Like other multidrug-resistant pathogens, the inherent antibiotic resistance of B. pseudomallei impedes treatment and hi...