Azacitidine Omega-3 Self-Assemblies: Synthesis, Characterization, and Potent Applications for Myelodysplastic Syndromes

• Main Authors: Milad Baroud (Author), Elise Lepeltier (Author), Yolla El-Makhour (Author), Nolwenn Lautram (Author), Jerome Bejaud (Author), Sylvain Thepot (Author), Olivier Duval (Author)
• פורמט: ספר
• יצא לאור: MDPI AG, 2021-12-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

5-Azacitidine, a cytidine analogue used as a hypomethylating agent, is one of the main drugs for the treatment of myelodysplastic syndromes (MDSs) and acute myeloid leukemia (AML) in the elderly. However, after administration, it exhibits several limitations, including restricted diffusion and cellu...