"Omics" data integration and functional analyses link Enoyl-CoA hydratase, short chain 1 to drug refractory dilated cardiomyopathy

• Main Authors: Nzali V. Campbell (Author), David A. Weitzenkamp (Author), Ian L. Campbell (Author), Ronald F. Schmidt (Author), Chindo Hicks (Author), Michael J. Morgan (Author), David C. Irwin (Author), John J. Tentler (Author)
• Format: Book
• Published: BMC, 2018-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Large-scale "omics" datasets have not been leveraged and integrated with functional analyses to discover potential drivers of cardiomyopathy. This study addresses the knowledge gap. Methods We coupled RNA sequence (RNA-Seq) variant detection and transcriptome profiling...